The cult-classic returns to terrorize 1950s Earth in Destroy All Humans!, a faithfully rebuilt remake of the legendary alien invasion action-adventure. Stepping into the role of the acerbic and powerful alien Crypto-137, players are tasked with a mission of cosmic proportions: harvest human DNA to ensure the survival of the Furon Empire and bring the US government to its knees. Whether you are navigating the streets on foot or raining destruction from your flying saucer, this remake delivers a hilarious, high-octerb scale assault on humanity.

An Intergalactic Invasion in 1950s America

Set against the backdrop of 1959 America, the story follows Crypto-137 as he embarks on a rescue mission to find his predecessor, Cryptosporidium-136. Under the command of the eccentric Orthopox (Pox), players must navigate a world of retro aesthetics and mid-century charm while executing much darker objectives. The plot is driven by the Furon need for DNA; due to the overuse of nuclear weapons, the Furon lineage faces extinction, making the harvest of human brain stems a high-stakes necessity.

The game seamlessly blends mission-based progression with open exploration. Players can traverse beautifully remastered cities using a jetpack or engage in large-scale warfare from their saucer. While many missions focus on direct destruction, others require stealth and subterfuge to learn the secrets of human civilization without being detected.

Gameplay Mechanics and Alien Arsenal

Destroy All Humans! features a satisfying gameplay loop centered around upgrading your capabilities to handle increasingly difficult challenges. As you progress from the quiet outskirts of Turnipseed Farm to intense urban showdowns, you can spend collected currency to enhance both Crypto’s personal abilities and the saucer's weaponry.

  • Psychic Abilities: Utilize psychokinesis to toss enemies and objects around, or use the Holobob to scan humans and adopt their appearance. Mastering the Holobob is essential for infiltrating human society, though players must be careful not to act too suspiciously or fail to scan enough minds.
  • Iconic Weaponry: Unleash havoc with a variety of bizarre alien tools, including the Disintegrator Ray, the Zap-O-Matic, the Abduct-O-Beam, and the infamous Anal Probe Gun.
  • Vehicular Destruction: Take to the skies in your flying saucer to obliterate primitive architecture and wipe out entire squads of humans from above.
  • Challenges and Replayability: Beyond the main campaign, players can engage in extra challenges—such as specific kill methods or stealth runs—and use an "explore mode" to wreak havoc in unlocked locations without mission constraints.

A Remastered Experience

Rebuilt from the ground up, this version offers a fresh look at the 2005 original with refined controls and expanded flexibility in abilities. A standout addition for long-time fans is the inclusion of the Lost Mission of Area 42, a previously unreleased piece of story content that was cut from the original release.

While the game maintains its signature comedic tone—filled with witty banter between Crypto and Pox and plenty of pop-culture nods—it also offers a much more polished experience. The remake is designed for players who enjoy high-concept sci-fi comedy, fans of classic "little green men" tropes, and anyone looking for an action-packed escape that doesn't take itself too seriously.